Prince Harry and Meghan Markle, the Duke and Duchess of Sussex, have been targeted by the creators of the long-running Comedy Central show South Park, according to a teaser clip for the show’s latest episode.

The episode, titled The Worldwide Privacy Tour, sees the Prince of Canada and his wife attempting to find privacy in a small mountain town.

In the clip, Kyle expresses his frustration at hearing about the couple, saying, “It's seriously driving me crazy, I'm sick of hearing about them, but I can't get away from them.

They're everywhere, in my fucking face.”

His friend Stan replies, “Look Kyle, we just kinda don't care about some dumb prince and his stupid wife.”

With nearly 1.5 million viewers per episode, it's likely that many people share this sentiment.

This comes after Prince Harry recently wrapped up the press tour for his memoir Spare, and amidst the launch of the couple's Netflix docuseries Harry and Meghan, as well as Meghan's podcast Archetypes.

Despite their requests for privacy, the couple continues to be in the public eye.

The American media's response to Prince Harry and Meghan Markle has changed drastically since their interview with Oprah Winfrey just under two years ago.

Following the release of Harry's memoir, the couple's popularity has plummeted in both the UK and the US.

Harry's bombshells, including revealing private conversations with family members, details about his military experience, and intimate information about his health, have left him open to ridicule.

After their interview with Oprah Winfrey, in which they made serious claims about the royal family, the fallout was significant, leading to a rare statement from the Queen.

However, the mocking following the release of Spare has been seen across the entertainment media spectrum in the US.

Late-night talk shows have parodied readings from the book, and award show hosts have made jokes at the couple's expense.

According to commentator Kevin O'Sullivan, Americans are getting tired of the couple's complaints.

He believes that the story about Harry losing his virginity in a field has spoiled the royal fairy tale for Americans.

Polls show that Meghan and Harry's popularity is plummeting in the US.

A recent survey by Redfield and Wilton for Newsweek showed that Prince Harry's favorability rating dropped 45 points from 38 in December to minus 7 in January, while Meghan dropped 36 points from 23 in December to minus 13 in the latest poll.

It remains to be seen how the couple will respond to this latest round of criticism.

With their continued efforts to maintain privacy, it's possible that they will retreat even further from the public eye.

However, with the media's continued interest in their lives, it's unlikely that they will be able to completely disappear from the spotlight.

In conclusion, Prince Harry and Meghan Markle have been the subject of ridicule and criticism in the US media following the release of Harry's memoir.

Their popularity has plummeted, and polls show that many Americans are tired of hearing about them.

Despite their efforts to maintain privacy, the couple continues to be in the public eye.

It remains to be seen how they will respond to this latest round of criticism, but it's clear that they will not be able to completely disappear from the spotlight.